HumanNeuroblastomacellline
Passage:41
1.5Mill.cells/ml;1.5ml
ProductInfo:
HumanNeuroblastomacelllineSH-SY5Y
Organism:Homosapiens(human)
Age:4yearsold
Gender:Female
Tissue:Brain(frommetastaticsite:bonemarrow)
Morphology:Thecellsgrowasclustersofneuroblasticcellswithmultiple,short,finecellprocesses(neurites).Cellswillaggregate,formclumpsandfloat;aconfluentmonolayerisnotformed.
Celltype:Neuroblast(neuroblastoma)
GrowthProperties:Looselyadherent;formclumpsathighcelldensity
Description:SH-SY5Yisoneofthreeseriallyisolatedneuroblastclones(SH-SY,SH-SY5,SH-SY5Y)ofthehumanneuroblastomacelllineSK-N-SHwhichwasestablishedin1970fromametastaticbonetumor.Thecellsexhibitmoderatelevelsofdopaminebetahydroxylaseactivity.TheycanconvertglutamatetotheneurotransmitterGABA.SH-SY5Ycellshaveareportedsaturationdensitygreaterthan1x106cells/cm2.Thelossofneuronalcharacteristicshasbeendescribedwithincreasingpassagenumbers(approx.passage20).NeuronalMarkersoruptakeofnoradrenalinshouldbedeterminedroutinely.Itisrecommendednottouseatpassagenumbershigherthan20unlessneuronalcharacteristicsarecontrolled.
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ProductName:SH-SY5Y
ProductCode:300154
Size:cryovial
StoreTemperature:-196°C
ShipTemperature:-70°C
UNSPSCCode:41106514
