HumanColonCarcinomacellline
Passage:37
Frozen,3Mill.cells/ml,1.5ml
ProductInfo:
HumanColonCarcinomacelllineLS-513
Organism:Homosapiens(human)
Ethnicity:Caucasian
Age:63years
Gender:Male
Tissue:Colorectalcarcinoma,cecum,Dukes"typeC
Morphology:Epithelial
GrowthProperties:Monolayer,adherent
Description:LS-513isacolorectalcarcinomacelllineisolatedin1985fromaprimarytumorbiopsyfroma63yearoldCaucasianmalepatientdiagnosedwithaDukes"CmucinsecretingcecaltumorlocatedattheBauhinvalve.Approximately50%ofLS-513cellsexpresssurfacecarcinoembryonicantigen(CEA).LS-513cellsexpressthemajorhistocompatibility(MHC)classIantigensHLAandbeta2microglobulin.MHCclassIIantigens(HLA-DR,DQ,andDPwerenotdetected).TGFbeta-1isinhibitoryforproliferationofLS-513cells,whereasTGFbeta-2hasnoeffectonthegrowthofthesecells.LS-513cellsare100-foldlesssensitivetoTGFbeta-1thantheLS-1034(ATCCCRL-2158)cellline.LS-513cellsaremultidrugresistant(MDR)andaretumOrigenicinnudemice.Colonyformingefficiencywas30%inmethylcellulose.
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ProductName:LS-513
ProductCode:300457
Size:cryovial
StoreTemperature:-196°C
ShipTemperature:-70°C
UNSPSCCode:41106514
